A strategy to determine operating parameters in tissue engineering hollow fiber bioreactors

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A strategy to determine operating parameters in tissue engineering hollow fiber bioreactors

The development of tissue engineering hollow fiber bioreactors (HFB) requires the optimal design of the geometry and operation parameters of the system. This article provides a strategy for specifying operating conditions for the system based on mathematical models of oxygen delivery to the cell population. Analytical and numerical solutions of these models are developed based on Michaelis-Ment...

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ژورنال

عنوان ژورنال: Biotechnology and Bioengineering

سال: 2011

ISSN: 0006-3592

DOI: 10.1002/bit.23062